Unusual Suspects

A 40-year-old mother disappears from her home in the middle of the night, and police chase multiple leads before coming up empty. Almost a year goes by until they investigate a very unlikely suspect - a high-school neighbor with an affinity for older women. Then, a teenage boy is murdered in his home and detectives believe his campaign against teen gang activity led to his death. But the community is horrified when police arrest one of their "model citizens" for ordering the hit.

In 1996, teenaged Joey Martin sneaks out of his bedroom window to watch a comet from a cabin in the woods-and disappears. Despite multiple leads, there is no sign of Joey until 2008 when a young detective uncovers the shocking story of Joey's fate.

Season 3 premiere. An attack on a Pennsylvania family that left only one survivor is discussed.

The 1995 death of a Chicago woman whose body was found on a Wisconsin highway is detailed in the Season 4 premiere.

The fifth season opens with a case involving a high-school girl who was murdered in 1985.

The Season 6 opener features a serial-rapist case in Reno.

Shortly before Thanksgiving, a Philadelphia suburb is rocked by the murder of 67-year-old Alice Hufnagle.

The murder of a popular young woman in Lancaster County, Pa., is investigated.